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By Suna F. Kiraç

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15) vs. 1 vs. 7% vs. 31 Table 5. 3 Acute coronary syndromes – ST elevation ACS The cornerstone of management in ST elevation ACS is the timely restoration of flow in the infarct related artery. The accepted strategies for reperfusion include primary PCI and thrombolysis. If available within a timely fashion from an experienced team, urgent coronary angiography and primary PCI offers better patient outcomes than thrombolysis in STEACS. In addition, primary PCI is recommended in patients with cardiogenic shock or contraindication to thrombolysis.

6, (December 1995) pp. 673682, ISSN 1074-7613 Wu, XX, et al. (2004). TRAIL and chemotherapeutic drugs in cancer therapy. Vitam Horm, Vol. 67, No. (April 2004) pp. 365-383, ISSN 0083-6729 Zauli, G, et al. (2003). Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sequentially upregulates nitric oxide and prostanoid production in primary human endothelial cells. Circ Res, Vol. 92, No. 7, (March 2003) pp. 732-740, ISSN 1524-4571 3 Indications for Coronary Angiography Karl Poon and Darren Walters The Prince Charles Hospital Australia 1.

Based on subgroup analysis on the TIMACS study in which patients with a GRACE score >140 39 Indications for Coronary Angiography benefited most from an early invasive strategy, this group of high risk patients would benefit from prompt (<24 hours) coronary angiography. Study design Median Primary early vs. endpoint Late difference (hrs) TACTICS NSTEACS Angiography 22hrs vs. 6 month death, TIMI 18 4-48 vs. 4 hrs vs. 30 day death or ISARCOOL < 6 hrs vs. > 86 hrs large MI (2003) 72 hrs TIMACS NSTEACS, Angiography 14 hrs vs.

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